(2) Hughes Bazura
(3) Rafli Susanto
(4) Theresia Saurina Febriadella Hutabarat
(5) Yutha N Manda
(6) Nanda Pratiwi
*corresponding author
AbstractThis study looks at how red betel (Piper crocatum) extract can help keep women's reproductive health in good condition using natural methods. The research used a descriptive qualitative approach, mainly by looking at existing scientific articles and data from journals and databases between 2015 and 2025. The focus was on finding out which active ingredients are in red betel, how they fight bacteria, and why they might be useful in preventing infections in the female reproductive system. The research shows that red betel has compounds like flavonoids, alkaloids, tannins, and phenolics that work together to stop harmful bacteria from growing, especially Staphylococcus aureus and Pseudomonas aeruginosa. These compounds fight bacteria in several ways, such as breaking down the bacterial cell walls, stopping important enzymes from working, and messing up the bacteria's energy processes. Studies also show that using red betel in the form of a decoction can help reduce symptoms like vaginal discharge while keeping the good bacteria in the vagina balanced. Compared to man-made antiseptics, red betel has similar antibacterial effects but causes less irritation and is less likely to lead to bacteria becoming resistant. This makes it a promising option for a safe and eco-friendly natural alternative in feminine hygiene and women's health care. More research is needed to find the best way to extract these compounds and to test their effectiveness through proper clinical studies. Keywordsantibacterial activity, Piper crocatum, red betel, reproductive health, vaginal infection
|
DOIhttps://doi.org/10.57235/qistina.v4i2.7286 |
Article metrics10.57235/qistina.v4i2.7286 Abstract views : 0 | PDF views : 0 |
Cite |
Full Text Download
|
References
aprianisa, T., Novianti, N., Maryani, D., Suriyati, S., & Rachmawati, R. (2023). Efektivitas Air Rebusan Daun Sirih Merah (Piper Crocatum) Terhadap Keputihan Pada Wanita Usia Subur Di Puskesmas Telaga Dewa Kota Bengkulu. Journal Of Midwifery, 11(2), 298–304. https://doi.org/10.37676/jm.v11i2.5117
Ayuningtyas, D., Dewi, R., Sari, P., & Larasati, T. A. (2025). Tinjauan Pustaka : Mekanisme Bacterial Vaginosis dalam Infeksi Intrauterin dan Dampaknya terhadap Kesehatan Reproduksi Wanita 1 Program Literature Review : Mechanism of Bacterial Vaginosis in Intrauterine Infection and Its Impact on Women ’ s Reproductive. Medula, 14 (11), 2025–2031.
Chaudhary, N., Kalyan, R., Singh, M., Agarwal, J., & Qureshi, S. (2019). Prevalence of reproductive tract infections in women attending a tertiary care center in Northern India with special focus on associated risk factors. Indian Journal of Sexually Transmitted Diseases and AIDS, 40(2), 113–119. https://doi.org/10.4103/ijstd.IJSTD_17_16
Laswini, I. W., & Neney, A. (2022). Pengetahuan, Sikap, dan Sumber Informasi Dengan Perilaku Personal Hygiene Saat Menstruasi Pada Remaja Putri. SIMFISIS Jurnal Kebidanan Indonesia, 2(1), 228–236. https://doi.org/10.53801/sjki.v2i1.55
Lestari, S., Kurnia, D., Mayanti, T., & Heliawati, L. (2024). Antimicrobial Activities of Stigmasterol from Piper crocatum in Vitro and in Silico. Journal of Chemistry, 2024. https://doi.org/10.1155/2024/2935516
Manaf, S. A., & Novemi. (2024). The effectiveness of using red betel leaf (Piper ornatum) infusion compared to binahong leaf (Anredera cordifolia) infusion in healing external genital infections. Science Midwifery, 12(1), 2721–9453.
Marliana, E., Setyaningrum, T., & Suwardi. (2022). Pertumbuhan Stek Batang Sirih Merah ( Piper crocatum. Jurnal Agroteknologi Vol., 6 (1), 33–41.
Marwahti, S., Kabuhung, E. I., & Salmarini, D. D. (2022). Penggunaan Rebusan Daun Sirih Sebagai Intervensi Non Farmakologi Untuk Mengurangi Keputihan Pada Wanita. Proceeding of Sari Mulia University Midwifery National Seminars, 4(01), 254–263.
Mu’minah, I., Purwo Aniarti, R., & Atmarina Yuliani, D. (2023). Upaya Wanita Usia Subur Dalam Mencegah Permasalahan Kesehatan Reproduksi Di Wilayah Kerja Puskesmas Kalibagor Kabupaten Banyumas. INVOLUSI: Jurnal Ilmu Kebidanan, 13(1), 24–29. https://doi.org/10.61902/involusi.v13i1.553
Mukafiah, N., & Sulistyani, N. (2022). Study of Antibacterial Activity of Green Betel Leaf (Piper betle L.) and Red Betel Leaf (Piper Crocatum L.) Extract Against Pseudomonas Aeruginosa Bacteria. Farmasains : Jurnal Farmasi Dan Ilmu Kesehatan, 7(1), 47–54. https://doi.org/10.22219/farmasains.v7i1.17379
Pascawati, R., & Hidayanti, D. (2024). Efektivitas Ekstrak Daun Sirih Merah Terhadap Jumlah Koloni Bakteri Pada Remaja Perempuan Yang Mengalami Keputihan. Media Penelitian Dan Pengembangan Kesehatan, 34(4), 918–926. https://doi.org/10.34011/jmp2k.v34i4.2394
Purwanti, R., Prihartanti, N. G., & Lestar, R. H. (2022). Effectiveness Decoction Of Red Betel Leaves (Piper Crocantum) Against Decreased Symptoms Of Fluor Albus In High School Girls Efektivitas. 05, 146–151. https://doi.org/10.20473/jvhs.V5.I3.2022.146-151
Puspita, P. J., Safithri, M., & Sugiharti, N. P. (2018). Antibacterial Activities of Sirih Merah ( Piper crocatum ) Leaf Extracts. Current Biochemistry, 5(3), 1–10.
Salamah, Maryanti, Sari, R. I., Andriyani, A., Zaitun, Nurlaili, H., Rohani, S., Rachmawati, F., Lathifah, N. S., Sunarsih, Nurliyani, & Mariza, A. (2024). Mengenal Kesehatan Reproduksi Pada Wanita. TAHTA MEDIA GROUP.
Wulandari, E. S., & Herlina, P. A. (2025). The Effectiveness of Red Piper Crocatum as a Natural Antiseptic in Reducing Fluor Albus Symptoms in Women of Reproductive Age. Medical And Health Science Journal, 09 (01), 2–6.
Zulkarnain, A. A. S. D., Narmada, I. B., & Ardani, I. G. A. W. (2023). The antibacterial activity of red betel ( Piper crocatum ) leaf extract toward Staphylococcus aureus. Indonesian Journal of Dental Medicine, 6(2), 70–73.
Refbacks
- There are currently no refbacks.
Copyright (c) 2025 Amkani Angelita Pakpahan, Hughes Bazura, Rafli Susanto, Theresia Saurina Febriadella Hutabarat, Yutha N Manda, Nanda Pratiwi

This work is licensed under a Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License.






















Download